Portal venous thrombosis (PVT) has incidence up to 1-4%. PVT can occur early within a month after transplant or late after a month of transplantation. Early PVT has a poor prognosis, leading to graft failure in majority of the cases.
Post Liver transplant acute PVT is not easy to treat, because of difficult alternative portal hepatic inflow establishment.
Here, this is a unique case of thrombolysis of huge acute PVT in post-liver transplant patient. Thrombolysis was done through a rare technique of per-cutaneous trans-splenic vein access.
The per-cutaneous trans- splenic vein approach based thrombolysis described here in our report, is very helpful because it minimize the potential risk of graft loss, avoids re-exploration and has a very low risk of bleeding in these post–liver transplant recipients.